1. Mandatory Disciplines
Biostatistics (2 Credit Units, 30 Credit Hours)
Syllabus: Fundamentals of scientific methodology. Experimental error. Graphical representation of data. Probability and random sampling. Distributions. Principles of inference and statistical estimation. Significance tests and curve fitting.
Teaching Internship – Master’s (2 Credit Units, 30 Credit Hours)
Syllabus: Participation of the graduate in theoretical and practical courses in undergraduate courses. Application of modern methods and techniques that allow training and practice in the teaching of undergraduate subjects, seeking to highlight aspects such as course planning and classes, audiovisual techniques used in lectures, seminars, symposia, guided studies and training in techniques laboratories employed in practical classes that can increase the performance of learning and make teaching more creative by the greater offer of chances of rediscovery.
Scientific research methodology (2 Credit Units, 30 Credit Hours)
Syllabus: The development of scientific knowledge through research. Characteristic of scientific research. Elaboration of the research from its project until the final presentation of the results. Main methods and techniques used by the researcher. The ethics of research.
Seminars on Pharmaceutical Sciences (2 Credit Units, 30 Credit Hours)
Syllabus: Presentation of seminars related to research in Pharmaceutical Sciences, by students of the Pharmaceutical Sciences Graduate Program regarding the objectives and methodology contained in their dissertation project.
2. Elective Disciplines
Pharmaceutical Assistance (2 Credit Units, 30 Credit Hours)
Syllabus: This subject aims to discuss pharmaceutical assistance from the perspective of the user in the community. It is the objective of this discipline to develop communication skills, group work and use scientific references in drug management and its rational use.
Microbiological Evaluation of Medications (2 Credit Units, 30 Credit Hours)
Syllabus: Primary and secondary standards of biological substances, preservative efficacy tests, sterile product analysis, in vivo and in vitro pyrogen test, microbiological assay of antibiotics, in vivo and in vitro toxicity tests, validation of sterilization processes, applied legislation to the biological and microbiological quality control of medicines.
Pharmaceutical Botany (2 Credit Units, 30 Credit Hours)
Syllabus: To present basic instruments for quality control of vegetable raw material. External and internal morphology and pharmaceutical applications of root, stem, leaf, fruit and seed. Notions of systematics and phytogeography. Characterization and examples of the main pharmacological interest taxa. External and internal morphology and pharmaceutical applications of root, stem, leaf, fruit and seed. Notions of systematics and phytogeography. Characterization and examples of the main pharmacological interest taxa.
Quality of Medicines Control (3 Credit Units, 45 Credit Hours)
Syllabus: Provide theoretical subsidies for the evaluation of the quality of pharmaceuticals and correlates through qualitative and quantitative analysis.
Pharmacological Testing (2 Credit Units, 30 Credit Hours)
Syllabus: Assembly by the students or demonstration by the professors of various preparations commonly used in Pharmacology, with emphasis on the methodologies used in the routine of the laboratories. From the results, pharmacological parameters will be obtained, discussion of the advantages and limitations of each methodology as well as pharmacological and statistical concepts that can be visualized in these experiments.
Strategies for Structural Identification of Natural Products Through 1D and 2D NMR (3 Credit Units, 45 Credit Hours)
Syllabus: Nuclear Magnetic Resonance Spectrometry 1D: Nuclear Magnetic Resonance of Hydrogen, Nuclear Magnetic Resonance of Carbon and Distortionless Enhancement by Polarization Transfer (DEPT). Signals characteristic of the main PN classes. COSY, HMBC and HSQC 2D Nuclear Magnetic Resonance Spectrum Interpretation Strategies.
Dry Extracts of Plant Origin (2 Credit Units, 30 Credit Hours)
Syllabus: Phytotherapeutics, production chain, economic aspects. Drying project: Methodology to manage research and development projects focusing on phytotherapeutic products. Obtaining and characterization of plant material. Methods of stabilizing, drying and processing of plant material. Fluid extracts: extractive methods and control of extraction processes. Obtaining, characterization and standardization of the dried extracts. Applications of the dried extracts in Phytopharmaceutical Technology.
Plant Extracts, Extractive Processes and Applications in Pharmacotechnics (3 Credit Units, 45 Credit Hours)
Syllabus: Obtaining, processing and characterization of the material; methods of stabilizing and drying the plant material; plant extracts; extractive operations: maceration, percolation, infusion, decoction, digestion, chemical and physicochemical characterization of vegetal extracts, applications in
Advanced Pharmacognosy (2 Credit Units, 30 Credit Hours)
Syllabus: Medicinal plants, active principles and phytocomplexes. Desiccation, conservation and use of medicinal plants. Popular approach combined with scientific approach. Pharmacognostic control of vegetables, drugs and herbal intermediates.
Pharmacology of Parasitic Diseases (3 Credit Units, 45 Credit Hours)
Syllabus: Neglected diseases; Pharmacological treatments of Malaria; Mechanisms of resistance of Plamodium falciparum; Experimental models for research of new drugs in sensitive and chloroquine resistant isolates, multiresistant; Pharmacological treatments of visceral and integument Leishmania; Mechanisms of Leishmania resistance; Experimental models for research of new drugs with anti-leishmania activity; Pharmacological treatments of Chagas' disease; Experimental models for research of new drugs with anti-T. cruzi activity; Evaluation of the efficacy of vaccines in protozooses.
General Pharmacology (3 Credit Units, 45 Credit Hours)
Syllabus: Concepts and general principles of pharmacology. General pharmacology (principles, absorption, distribution, metabolism and elimination of drugs). Pharmacodynamics. Pharmacology of the autonomic nervous system (cholinergic and adrenergic agonists and their respective antagonists: anticholinesterases). Pharmacology of the cardiovascular system (antihypertensive drugs and cardiotonic glycosides). Pharmacology of the inflammatory process and anti-inflammatory drugs, such as glucocorticoids and nonsteroidal anti-inflammatory drugs.
Advanced Pharmacotechnics (2 Credit Units, 30 Credit Hours)
Syllabus: The discipline will discuss aspects related to drug planning and development; will discuss the major modified release systems.
Phytopharmacy (2 Credit Units, 30 Credit Hours)
Syllabus: Phytotherapy; Phytomedications; Phytopharmaceuticals: origin, structure and activity.
Advanced Phytochemistry (3 Credit Units, 45 Credit Hours)
Syllabus: Phytochemical research methods. Sources of information on plant species of therapeutic and industrial interest. Biosynthesis of secondary metabolites of plant origin. Chemical taxonomy. Methods of structural determination of organic compounds.
Fundamentals of Teaching Practice (2 Credit Units, 30 Credit Hours)
Syllabus: The discipline aims to analyze higher education in the contemporary world and the process of constructing the identity of the teaching university researcher. It problematizes the process of teaching and learning from different pedagogical conceptions historically constituted in the educational process of the country. Conceiving teaching as a socio-reflexive and libertarian practice and the teacher-facilitator training from the perspective of teacher professionalization. It presents the methodological components, anchored in the active methodologies and in the process of planning and permanent evaluation, based on the Curricular Guidelines of Higher Education in Pharmacy and the Pedagogical Project of the Course.
Analytical Methods Spectrometric (3 Credit Units, 45 Credit Hours)
Syllabus: Phytochemical research methods. Sources of information on plants of therapeutic and industrial interest. Biosynthesis of secondary metabolites of plant origin. Chemical taxonomy. Methods of structural determination of organic compounds.
Chromatographic Methods (3 Credit Units, 45 Credit Hours)
Syllabus: Chromatography on paper. Thin layer chromatography. Chromatography by adsorption. Ion exchange chromatography. Chromatography by exclusion. Chromatography by bioaffinity. Gas chromatography. Other methods of separation.
Advanced Pharmaceutical Chemistry (2 Credit Units, 30 Credit Hours)
Syllabus: Study of the principles of the relationship between chemical structure and toxicity and pharmacological activity of bioactive substances, definition of toxicochemical and pharmacophoric grouping; importance of the metabolism phases in toxicity and potential drug activity. Biotransformations of reactive species. Structural characteristics of selective biocoordination agents.
Organic chemistry I (2 Credit Units, 30 Credit Hours)
Syllabus: Structural Theory. Intermolecular forces. Effects of structure on physical and chemical properties. Structure of saturated and unsaturated, alicyclic and cyclic hydrocarbons. Conformational analysis. Functional groups formed by single bonds, functional groups containing carbonyl, aromatic compounds and aromaticity and groups containing heteroatoms physical, chemical and nomenclature properties. Stereochemistry. Acidity and basicity of organic compounds. Intermediates involved in organic reactions.
Medicine Carrier Systems (3 Credit Units, 45 Credit Hours)
Syllabus: This subject aims to address the theoretical content, development and applications of new pharmaceutical forms of innovative technology. In this way, students will acquire more knowledge of the nanotechnology era in health.
Pharmaceutical technology (2 Credit Units, 30 Credit Hours)
Syllabus: Preformulation of pharmaceutical forms; technology of dispersed pharmaceutical forms; technology of parenteral preparations; technology of solid and semi-solid dosage forms; drug stability; production standards.
Topics in Drugs and Medications (3 Credit Units, 45 Credit Hours)
Syllabus: The discipline deals with varied and up-to-date topics on drugs and medicines.
Topics in Pharmacovigilance and Epidemiology (2 Credit Units, 30 Credit Hours)
Syllabus: Identification of types, mechanism of production of clinical diagnosis of adverse reactions produced by medicines (ADR). Study of the spontaneous reporting systems of ADRs and pharmacovigilance programs.
Toxicology (3 Credit Units, 45 Credit Hours)
Syllabus: Toxicological classification, toxicity assessment, toxicity of drugs used in tropical diseases, toxicodynamics, toxic methemoglobinizing agents, heavy metals, plants toxic to humans, venomous animals.